Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases

The synthesis of the catecholic siderophore bacillibactin is accomplished by the nonribosomal peptide synthetase (NRPS) encoded by the dhb operon. DhbE is responsible for the initial step in bacillibactin synthesis, the activation of the aryl acid 2,3-dihydroxybenzoate (DHB). The stand-alone adenyla...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	May, Jürgen J., Kessler, Nadine, Marahiel, Mohamed A., Stubbs, Milton T.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129408/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12221282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182156699
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