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RecX protein abrogates ATP hydrolysis and strand exchange promoted by RecA: Insights into negative regulation of homologous recombination

In many eubacteria, coexpression of recX with recA is essential for attenuation of the deleterious effects of recA overexpression; however, the molecular mechanism has remained enigmatic. Here, we show that Mycobacterium tuberculosis RecX binds directly to M. tuberculosis RecA as well as M. smegmati...

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Bibliografiske detaljer
Main Authors: Venkatesh, R., Ganesh, N., Guhan, N., Reddy, M. Sreedhar, Chandrasekhar, T., Muniyappa, K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129403/
https://ncbi.nlm.nih.gov/pubmed/12218174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192178999
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