RecX protein abrogates ATP hydrolysis and strand exchange promoted by RecA: Insights into negative regulation of homologous recombination

In many eubacteria, coexpression of recX with recA is essential for attenuation of the deleterious effects of recA overexpression; however, the molecular mechanism has remained enigmatic. Here, we show that Mycobacterium tuberculosis RecX binds directly to M. tuberculosis RecA as well as M. smegmati...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Venkatesh, R., Ganesh, N., Guhan, N., Reddy, M. Sreedhar, Chandrasekhar, T., Muniyappa, K.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129403/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12218174/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192178999
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