Crystal structure of calcineurin–cyclophilin–cyclosporin shows common but distinct recognition of immunophilin–drug complexes
Calcineurin, a Ca(2+)/calmodulin-dependent protein phosphatase, is the common target for two immunophilin–immunosuppressant complexes, cyclophilin A–cyclosporin A (CyPA-CsA) and FKBP–FK506. How the two structurally distinct immunophilin–drug complexes bind the same target has remained unknown. We re...
সংরক্ষণ করুন:
| প্রকাশিত: | Proc Natl Acad Sci U S A |
|---|---|
| প্রধান লেখক: | , , , , , , |
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
National Academy of Sciences
2002
|
| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12218175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192206699 |
| ট্যাগগুলো: |
কোনো ট্যাগ নেই, প্রথমজন হিসাবে ট্যাগ করুন!
|