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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Tissues from rhesus monkeys were screened by PCR for the presence of sequences homologous to known adeno-associated virus (AAV) serotypes 1–6. DNA spanning entire rep-cap ORFs from two novel AAVs, called AAV7 and AAV8, were isolated. Sequence comparisons among these and previously described AAVs rev...

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Autors principals: Gao, Guang-Ping, Alvira, Mauricio R., Wang, Lili, Calcedo, Roberto, Johnston, Julie, Wilson, James M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC129358/
https://ncbi.nlm.nih.gov/pubmed/12192090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182412299
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