Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

Tissues from rhesus monkeys were screened by PCR for the presence of sequences homologous to known adeno-associated virus (AAV) serotypes 1–6. DNA spanning entire rep-cap ORFs from two novel AAVs, called AAV7 and AAV8, were isolated. Sequence comparisons among these and previously described AAVs rev...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Gao, Guang-Ping, Alvira, Mauricio R., Wang, Lili, Calcedo, Roberto, Johnston, Julie, Wilson, James M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2002
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129358/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12192090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.182412299
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