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Short-term antigen presentation and single clonal burst limit the magnitude of the CD8+ T cell responses to malaria liver stages
Malaria sporozoites induce swift activation of antigen-specific CD8+ T cells that inhibit the intracellular development of liver-stage parasites. The length of time of functional in vivo antigen presentation, estimated by monitoring the activation of antigen-specific CD8+ T cells, is of short durati...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129352/ https://ncbi.nlm.nih.gov/pubmed/12185251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182189999 |
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