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Identification of the binding sites of regulatory proteins in bacterial genomes

We present an algorithm that extracts the binding sites (represented by position-specific weight matrices) for many different transcription factors from the regulatory regions of a genome, without the need for delineating groups of coregulated genes. The algorithm uses the fact that many DNA-binding...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Li, Hao, Rhodius, Virgil, Gross, Carol, Siggia, Eric D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129344/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12181488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.112341999
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