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Identification of the binding sites of regulatory proteins in bacterial genomes

We present an algorithm that extracts the binding sites (represented by position-specific weight matrices) for many different transcription factors from the regulatory regions of a genome, without the need for delineating groups of coregulated genes. The algorithm uses the fact that many DNA-binding...

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Detalhes bibliográficos
Main Authors: Li, Hao, Rhodius, Virgil, Gross, Carol, Siggia, Eric D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129344/
https://ncbi.nlm.nih.gov/pubmed/12181488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.112341999
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