Alcohol reversibly disrupts TNF-α/TACE interactions in the cell membrane

BACKGROUND: Alcohol abuse has long been known to adversely affect innate and adaptive immune responses and pre-dispose to infections. One cellular mechanism responsible for this effect is alcohol-induced suppression of TNF-α (TNF) by mononuclear phagocytes. We have previously shown that alcohol in p...

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Autors principals: Song, Kejing, Zhao, Xue-Jun, Marrero, Luis, Oliver, Peter, Nelson, Steve, Kolls, Jay K
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291403/
https://ncbi.nlm.nih.gov/pubmed/16246259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-123
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