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The plmS(2)-Encoded Cytochrome P450 Monooxygenase Mediates Hydroxylation of Phoslactomycin B in Streptomyces sp. Strain HK803

Streptomyces sp. strain HK803 produces six analogues of phoslactomycin (Plm A through Plm F). With the exception of Plm B, these analogues contain a C-18 hydroxyl substituent esterified with a range of short-alkyl-chain carboxylic acids. Deletion of the plmS(2) open reading frame (ORF), showing high...

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Detalhes bibliográficos
Main Authors: Ghatge, Mohini S., Reynolds, Kevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291264/
https://ncbi.nlm.nih.gov/pubmed/16291670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.23.7970-7976.2005
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