Generation and Characterization of p38β (MAPK11) Gene-Targeted Mice

p38 mitogen-activated protein kinases (MAPKs) are activated primarily in response to inflammatory cytokines and cellular stress, and inhibitors which target the p38α and p38β MAPKs have shown potential for the treatment of inflammatory disease. Here we report the generation and initial characterizat...

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Autors principals: Beardmore, Victoria A., Hinton, Heather J., Eftychi, Christina, Apostolaki, Maria, Armaka, Maria, Darragh, Joanne, McIlrath, Joanne, Carr, Julia M., Armit, Laura J., Clacher, Carol, Malone, Loraine, Kollias, George, Arthur, J. Simon C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291241/
https://ncbi.nlm.nih.gov/pubmed/16287858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10454-10464.2005
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