Hairless-Mediated Repression of Notch Target Genes Requires the Combined Activity of Groucho and CtBP Corepressors

Notch signal transduction centers on a conserved DNA-binding protein called Suppressor of Hairless [Su(H)] in Drosophila species. In the absence of Notch activation, target genes are repressed by Su(H) acting in conjunction with a partner, Hairless, which contains binding motifs for two global corep...

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Autores principales: Nagel, Anja C., Krejci, Alena, Tenin, Gennady, Bravo-Patiño, Alejandro, Bray, Sarah, Maier, Dieter, Preiss, Anette
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291231/
https://ncbi.nlm.nih.gov/pubmed/16287856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10433-10441.2005
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