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Tr-kit-induced resumption of the cell cycle in mouse eggs requires activation of a Src-like kinase
Microinjection in mouse eggs of tr-kit, a truncated form of the c-kit tyrosine kinase present in mouse spermatozoa, causes resumption of meiosis through activation of phospholipase Cγ1 (PLCγ1) and Ca(2+) mobilization from intracellular stores. We show that the Src-like kinase Fyn phosphorylates Tyr1...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129085/ https://ncbi.nlm.nih.gov/pubmed/12374739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf553 |
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