CD40 regulates the processing of NF-κB2 p100 to p52

The nf-kb2 gene encodes the cytoplasmic NF-κB inhibitory protein p100 from which the active p52 NF-κB subunit is derived by proteasome-mediated proteolysis. Ligands which stimulate p100 processing to p52 have not been defined. Here, ligation of CD40 on transfected 293 cells is shown to trigger p52 p...

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Main Authors: Coope, H.J., Atkinson, P.G.P., Huhse, B., Belich, M., Janzen, J., Holman, M.J., Klaus, G.G.B., Johnston, L.H., Ley, S.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129074/
https://ncbi.nlm.nih.gov/pubmed/12374738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf542
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