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Family-Based Tests of Association and Linkage That Use Unaffected Sibs, Covariates, and Interactions

We extend the methodology for family-based tests of association and linkage to allow for both variation in the phenotypes of subjects and incorporation of covariates into general-score tests of association. We use standard association models for a phenotype and any number of predictors. We then cons...

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Detalhes bibliográficos
Main Authors: Lunetta, Kathryn L., Faraone, Stephen V., Biederman, Joseph, Laird, Nan M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288113/
https://ncbi.nlm.nih.gov/pubmed/10677320
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