16α-Bromoepiandrosterone, an Antimalarial Analogue of the Hormone Dehydroepiandrosterone, Enhances Phagocytosis of Ring Stage Parasitized Erythrocytes: a Novel Mechanism for Antimalarial Activity

Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEA-S), which are the most abundant hormones secreted by the adrenal cortex and are present in plasma at approximately 6 μM, as well as their analogue, 16α-bromoepiandrosterone (EPI), exerted antimalarial activities against two chloroquine-sensitive P...

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Detalhes bibliográficos
Main Authors: Ayi, Kodjo, Giribaldi, Giuliana, Skorokhod, Aleksei, Schwarzer, Evelin, Prendergast, Patrick T., Arese, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128802/
https://ncbi.nlm.nih.gov/pubmed/12234842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.10.3180-3184.2002
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