Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region

Cis elements that mediate transcription factor binding are abundant within genomes, but the rules governing occupancy of such motifs in chromatin are not understood. The transcription factor GATA-1 that regulates red blood cell development binds with high affinity to GATA motifs, and initial studies...

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Main Authors: Im, Hogune, Grass, Jeffrey A., Johnson, Kirby D., Kim, Shin-Il, Boyer, Meghan E., Imbalzano, Anthony N., Bieker, James J., Bresnick, Emery H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287986/
https://ncbi.nlm.nih.gov/pubmed/16286657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506164102
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