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Hypoxia inducible factor 1α regulates T cell receptor signal transduction

Low oxygen pressures exist in many solid tissues, including primary and secondary lymphoid organs. One key element in cellular adaptation to hypoxia is induced expression of hypoxia inducible factor (Hif) 1α. Here, we have examined the effect of Hif-1α, isolated from the myriad other effects of hypo...

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Detalhes bibliográficos
Main Authors: Neumann, Aaron K., Yang, Jaeseok, Biju, Mangat P., Joseph, Suresh K., Johnson, Randall S., Haase, Volker H., Freedman, Bruce D., Turka, Laurence A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287984/
https://ncbi.nlm.nih.gov/pubmed/16286658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506070102
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