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Vhlh Gene Deletion Induces Hif-1-Mediated Cell Death in Thymocytes
The von Hippel-Lindau gene product (pVHL) targets the α subunit of basic helix-loop-helix transcription factor hypoxia-inducible factor (HIF) for proteasomal degradation. Inactivation of pVhl in the mouse germ line results in embryonic lethality, indicating that tight control of Hif-mediated adaptiv...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517905/ https://ncbi.nlm.nih.gov/pubmed/15456877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.9038-9047.2004 |
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