Endogenous Reactive Oxygen Species Is an Important Mediator of Miconazole Antifungal Effect

We investigated the significance of endogenous reactive oxygen species (ROS) produced by fungi treated with miconazole. ROS production in Candida albicans was measured by a real-time fluorogenic assay. The level of ROS production was increased by miconazole at the MIC (0.125 μg/ml) and was enhanced...

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Hlavní autoři: Kobayashi, Daisuke, Kondo, Kei, Uehara, Nobuyuki, Otokozawa, Seiko, Tsuji, Naoki, Yagihashi, Atsuhito, Watanabe, Naoki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
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Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128784/
https://ncbi.nlm.nih.gov/pubmed/12234832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.10.3113-3117.2002
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