Breaking an Absolute Species Barrier: Transgenic Mice Expressing the Mink PrP Gene Are Susceptible to Transmissible Mink Encephalopathy

Transmissible mink encephalopathy (TME) is a rare disease of the North American mink, which has never been successfully transmitted to laboratory mice. We generated transgenic mice expressing the mink prion protein (PrP) and inoculated them with TME or the mouse-adapted scrapie strain 79A. TME infec...

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Bibliografiske detaljer
Main Authors: Windl, O., Buchholz, M., Neubauer, A., Schulz-Schaeffer, W., Groschup, M., Walter, S., Arendt, S., Neumann, M., Voss, A. K., Kretzschmar, H. A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287601/
https://ncbi.nlm.nih.gov/pubmed/16282497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14971-14975.2005
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