Central Nervous System Pathology Caused by Autoreactive CD8(+) T-Cell Clones following Virus Infection

Theiler's murine encephalomyelitis virus (TMEV) causes a demyelinating disease in infected mice which has similarities to multiple sclerosis. Spleen cells from TMEV-infected SJL/J mice stimulated with antigen-presenting cells infected with TMEV resulted in a population of autoreactive CD8(+) cy...

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Bibliographic Details
Main Authors: Tsunoda, Ikuo, Kuang, Li-Qing, Kobayashi-Warren, Mikako, Fujinami, Robert S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287580/
https://ncbi.nlm.nih.gov/pubmed/16282464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14640-14646.2005
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