Pharmacokinetics and Pharmacodynamics of Gatifloxacin against Streptococcus pneumoniae and Staphylococcus aureus in a Granulocyte-Rich Exudate

The pharmacokinetics of gatifloxacin were assessed in serum and in skin blister fluid (SBF), as was the pharmacodynamic activity in SBF. Five hours after a single dose of gatifloxacin, SBF killed 2.5 logs of Streptococcus pneumoniae and 1.5 log of Staphylococcus aureus during a 2-h incubation ex viv...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Trampuz, Andrej, Laifer, Gerd, Wenk, Markus, Rajacic, Zarko, Zimmerli, Werner
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384378/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3630-3633.2002
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