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Resistance to β-Lactamase Inhibitor Protein Does Not Parallel Resistance to Clavulanic Acid in TEM β-Lactamase Mutants

In order to compare patterns of resistance to inhibition by clavulanic acid with patterns of resistance to inhibition by a β-lactamase inhibitor protein (BLIP), R164S, R244S, and R164S/R244S mutant forms of TEM β-lactamase were prepared by site-directed mutagenesis. When kinetic parameters were dete...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Schroeder, William A., Locke, Troy R., Jensen, Susan E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2002
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128715/
https://ncbi.nlm.nih.gov/pubmed/12384366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3568-3573.2002
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