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Constitutive High Expression of Chromosomal β-Lactamase in Pseudomonas aeruginosa Caused by a New Insertion Sequence (IS1669) Located in ampD

The expression of chromosomal AmpC β-lactamase in Pseudomonas aeruginosa is negatively regulated by the activity of an amidase, AmpD. In the present study we examined resistant clinical P. aeruginosa strains and several resistant variants isolated from in vivo and in vitro biofilms for mutations in...

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Main Authors: Bagge, Niels, Ciofu, Oana, Hentzer, Morten, Campbell, Joan I. A., Givskov, Michael, Høiby, Niels
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC128714/
https://ncbi.nlm.nih.gov/pubmed/12384343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3406-3411.2002
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