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A Test for Linkage and Association in General Pedigrees: The Pedigree Disequilibrium Test

Family-based tests of linkage disequilibrium typically are based on nuclear-family data including affected individuals and their parents or their unaffected siblings. A limitation of such tests is that they generally are not valid tests of association when data from related nuclear families from lar...

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Auteurs principaux: Martin, Eden R., Monks, Stephanie A., Warren, Liling L., Kaplan, Norman L.
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287073/
https://ncbi.nlm.nih.gov/pubmed/10825280
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