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Determination of Antibiotic Effect in an In Vitro Pharmacodynamic Model: Comparison with an Established Animal Model of Infection

Animal infection models have historically been used to study pharmacodynamic relationships. Similar results could theoretically be produced by using an in vitro pharmacodynamic model as an alternative to animal models. We compared the antibiotic effects of ticarcillin administered in various doses a...

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Autori principali: Bonapace, Charles R., Friedrich, Lawrence V., Bosso, John A., White, Roger L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC128701/
https://ncbi.nlm.nih.gov/pubmed/12384367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3574-3579.2002
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