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PKCɛ-mediated phosphorylation of vimentin controls integrin recycling and motility
PKCɛ controls the transport of endocytosed β1-integrins to the plasma membrane regulating directional cell motility. Vimentin, an intermediate filament protein upregulated upon epithelial cell transformation, is shown here to be a proximal PKCɛ target within the recycling integrin compartment. On in...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283946/ https://ncbi.nlm.nih.gov/pubmed/16270034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600847 |
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