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The structural basis of myotonic dystrophy from the crystal structure of CUG repeats
Myotonic dystrophy (DM) type 1 is associated with an expansion of (>50) CTG repeats within the 3′ untranslated region (UTR) of the dystrophin myotonin protein kinase gene (dmpk). In the corresponding mRNA transcript, the CUG repeats form an extended stem-loop structure. The double-stranded RNA of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1283809/ https://ncbi.nlm.nih.gov/pubmed/16269545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505873102 |
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