IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1β and IL-6 production through a caspase 1-dependent mechanism

The activation of innate immunity requires the amplification of signals induced by pattern-recognition receptors for bacterial products. We have investigated the role of the newly described cytokine IL-32 in the amplification of cytokine production induced by the two most clinically relevant familie...

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Detalhes bibliográficos
Main Authors: Netea, Mihai G., Azam, Tania, Ferwerda, Gerben, Girardin, Stephen E., Walsh, Mark, Park, Jong-Sung, Abraham, Edward, Kim, Jin-Man, Yoon, Do-Young, Dinarello, Charles A., Kim, Soo-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283464/
https://ncbi.nlm.nih.gov/pubmed/16260731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508237102
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