The ETV6-NTRK3 chimeric tyrosine kinase suppresses TGF-β signaling by inactivating the TGF-β type II receptor

Eitemau Tebyg

• Mutations in the SAM Domain of the ETV6-NTRK3 Chimeric Tyrosine Kinase Block Polymerization and Transformation Activity
  gan: Tognon, Cristina E., et al.
  Cyhoeddwyd: (2004)
• The Insulin-Like Growth Factor I Receptor Is Required for Akt Activation and Suppression of Anoikis in Cells Transformed by the ETV6-NTRK3 Chimeric Tyrosine Kinase
  gan: Martin, Matthew J., et al.
  Cyhoeddwyd: (2006)
• ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex
  gan: Li, Zhe, et al.
  Cyhoeddwyd: (2007)
• Mutation of the Salt Bridge-forming Residues in the ETV6-SAM Domain Interface Blocks ETV6-NTRK3-induced Cellular Transformation
  gan: Cetinbas, Naniye, et al.
  Cyhoeddwyd: (2013)
• An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases
  gan: Kleczko, Emily K., et al.
  Cyhoeddwyd: (2015)