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Effect of katG Mutations on the Virulence of Mycobacterium tuberculosis and the Implication for Transmission in Humans
The usefulness of isoniazid (INH), a key component of short-course chemotherapy of tuberculosis, is threatened by the emergence of drug-resistant strains of Mycobacterium tuberculosis with mutations in the katG gene. It is shown here that the most commonly occurring KatG mutation, where Ser 315 is r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128294/ https://ncbi.nlm.nih.gov/pubmed/12183541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.9.4955-4960.2002 |
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