Streptococcal Inhibitor of Complement Inhibits Two Additional Components of the Mucosal Innate Immune System: Secretory Leukocyte Proteinase Inhibitor and Lysozyme

Streptococcal inhibitor of complement (SIC) is a 31-kDa extracellular protein of a few, very virulent, strains of Streptococcus pyogenes (particularly M1 strains). It is secreted in large quantities (about 5 mg/liter) and inhibits complement lysis by blocking the membrane insertion site on C5b67. We...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Fernie-King, Barbara A., Seilly, David J., Davies, Alexandra, Lachmann, Peter J.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Assuntos:	Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183536/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4908-4916.2002
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