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Despite Transcriptional and Functional Coordination, Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Largely Reside in Distinct Lipid Microdomains in WISH Epithelial Cells

Cytokine-induced prostaglandin (PG) E(2) synthesis requires increased expression of cyclooxygenase-2 (COX-2) in human WISH epithelial cells. Recently, an inducible downstream PGE synthase (microsomal PGE synthase-1, mPGES-1) has been implicated in this inflammatory pathway. We evaluated cooperation...

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Bibliografiska uppgifter
Huvudupphovsmän: Ackerman, William E., Robinson, John M., Kniss, Douglas A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1282464/
https://ncbi.nlm.nih.gov/pubmed/15983118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.5A6710.2005
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