Increased Trypanosoma cruzi Invasion and Heart Fibrosis Associated with High Transforming Growth Factor β Levels in Mice Deficient in α(2)-Macroglobulin

Trypanosoma cruzi proteinases are involved in host cell invasion in human patients and in mouse models. In mice, murine α(2)-macroglobulin (MAM) and murinoglobulin are circulating plasma proteinase inhibitors that also have important roles in inflammation and immune modulation. To define their role...

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Pubblicato in:	Infect Immun
Autori principali:	Waghabi, M. C., Coutinho, C. M. L. M., Soeiro, M. N. C., Pereira, M. C. S., Feige, J.-J., Keramidas, M., Cosson, A., Minoprio, P., Van Leuven, F., Araújo-Jorge, T. C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.5115-5123.2002
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