The Enterococcus faecalis fsrB Gene, a Key Component of the fsr Quorum-Sensing System, Is Associated with Virulence in the Rabbit Endophthalmitis Model

We used a rabbit endophthalmitis model to explore the role of fsrB, a gene required for the function of the fsr quorum-sensing system of Enterococcus faecalis, in pathogenicity. A nonpolar deletion mutant of fsrB had significantly reduced virulence compared to wild type. Complementation of mutation...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Mylonakis, Eleftherios, Engelbert, Michael, Qin, Xiang, Sifri, Costi D., Murray, Barbara E., Ausubel, Frederick M., Gilmore, Michael S., Calderwood, Stephen B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12117982/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.8.4678-4681.2002
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