The Enterococcus faecalis fsrB Gene, a Key Component of the fsr Quorum-Sensing System, Is Associated with Virulence in the Rabbit Endophthalmitis Model

We used a rabbit endophthalmitis model to explore the role of fsrB, a gene required for the function of the fsr quorum-sensing system of Enterococcus faecalis, in pathogenicity. A nonpolar deletion mutant of fsrB had significantly reduced virulence compared to wild type. Complementation of mutation...

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Detalhes bibliográficos
Main Authors: Mylonakis, Eleftherios, Engelbert, Michael, Qin, Xiang, Sifri, Costi D., Murray, Barbara E., Ausubel, Frederick M., Gilmore, Michael S., Calderwood, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128160/
https://ncbi.nlm.nih.gov/pubmed/12117982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4678-4681.2002
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