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Developmental Exposure of Rats to Chlorpyrifos Elicits Sex-Selective Hyperlipidemia and Hyperinsulinemia in Adulthood

Developmental exposure to chlorpyrifos alters cell signaling both in the brain and in peripheral tissues, affecting the responses to a variety of neurotransmitters and hormones. We administered 1 mg/kg/day chlorpyrifos to rats on postnatal days 1–4, a regimen below the threshold for systemic toxicit...

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Detalhes bibliográficos
Main Authors: Slotkin, Theodore A., Brown, Kathleen K., Seidler, Frederic J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1281268/
https://ncbi.nlm.nih.gov/pubmed/16203236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.8133
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