ADP and Other Metabolites Released from Acanthamoeba castellanii Lead to Human Monocytic Cell Death through Apoptosis and Stimulate the Secretion of Proinflammatory Cytokines

Monocytes/macrophages are thought to be involved in Acanthamoeba infections. The aim of this work was to study whether soluble metabolites (ADP and other compounds) released by Acanthamoeba castellanii trophozoites could induce morphological and biochemical changes in human monocytic cells in vitro....

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Autores principales: Mattana, A., Cappai, V., Alberti, L., Serra, C., Fiori, P. L., Cappuccinelli, P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC128125/
https://ncbi.nlm.nih.gov/pubmed/12117953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4424-4432.2002
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