ADP and Other Metabolites Released from Acanthamoeba castellanii Lead to Human Monocytic Cell Death through Apoptosis and Stimulate the Secretion of Proinflammatory Cytokines

Monocytes/macrophages are thought to be involved in Acanthamoeba infections. The aim of this work was to study whether soluble metabolites (ADP and other compounds) released by Acanthamoeba castellanii trophozoites could induce morphological and biochemical changes in human monocytic cells in vitro....

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Detalhes bibliográficos
Main Authors: Mattana, A., Cappai, V., Alberti, L., Serra, C., Fiori, P. L., Cappuccinelli, P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128125/
https://ncbi.nlm.nih.gov/pubmed/12117953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4424-4432.2002
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