Synergic Effects of Mycoplasmal Lipopeptides and Extracellular ATP on Activation of Macrophages

Mycoplasmal lipopeptides S-(2,3-bispalmitoyloxypropyl)-CGDPKHSPKSF and S-(2,3-bispalmitoyloxypropyl)-CGNNDESNISFKEK activated a monocytic cell line, THP-1 cells, to produce tumor necrosis factor alpha. The activity of the lipopeptides was augmented by ATP in a dose-dependent manner. In addition, the...

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Hlavní autoři: Into, Takeshi, Fujita, Mari, Okusawa, Tsugumi, Hasebe, Akira, Morita, Manabu, Shibata, Ken-Ichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128035/
https://ncbi.nlm.nih.gov/pubmed/12065499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3586-3591.2002
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