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Homologues of the Caenorhabditis elegans Fox-1 Protein Are Neuronal Splicing Regulators in Mammals

A vertebrate homologue of the Fox-1 protein from C. elegans was recently shown to bind to the element GCAUG and to act as an inhibitor of alternative splicing patterns in muscle. The element UGCAUG is a splicing enhancer element found downstream of numerous neuron-specific exons. We show here that m...

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Autors principals: Underwood, Jason G., Boutz, Paul L., Dougherty, Joseph D., Stoilov, Peter, Black, Douglas L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280273/
https://ncbi.nlm.nih.gov/pubmed/16260614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.10005-10016.2005
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