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A Nuclear Surveillance Pathway for mRNAs with Defective Polyadenylation
The pap1-5 mutation in poly(A) polymerase causes rapid depletion of mRNAs at restrictive temperatures. Residual mRNAs are polyadenylated, indicating that Pap1-5p retains at least partial activity. In pap1-5 strains lacking Rrp6p, a nucleus-specific component of the exosome complex of 3′-5′ exonuclea...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1280253/ https://ncbi.nlm.nih.gov/pubmed/16260613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9996-10004.2005 |
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