RelB/p52 NF-κB Complexes Rescue an Early Delay in Mammary Gland Development in Transgenic Mice with Targeted Superrepressor IκB-α Expression and Promote Carcinogenesis of the Mammary Gland

Classical NF-κB (p65/p50) transcription factors display dynamic induction in the mammary gland during pregnancy. To further elucidate the role of NF-κB factors in breast development, we generated a transgenic mouse expressing the IκB-α S32/36A superrepressor (SR) protein under control of the mouse m...

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Autores principales: Demicco, Elizabeth G., Kavanagh, Kathryn T., Romieu-Mourez, Raphaëlle, Wang, Xiaobo, Shin, Sangmin R., Landesman-Bollag, Esther, Seldin, David C., Sonenshein, Gail E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280249/
https://ncbi.nlm.nih.gov/pubmed/16260626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.10136-10147.2005
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