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Adenovirus Exploits the Cellular Aggresome Response To Accelerate Inactivation of the MRN Complex

Results reported here indicate that adenovirus 5 exploits the cellular aggresome response to accelerate inactivation of MRE11-RAD50-NBS1 (MRN) complexes that otherwise inhibit viral DNA replication and packaging. Aggresomes are cytoplasmic inclusion bodies, observed in many degenerative diseases, th...

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Detalhes bibliográficos
Main Authors: Liu, Yue, Shevchenko, Anna, Shevchenko, Andrej, Berk, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280221/
https://ncbi.nlm.nih.gov/pubmed/16254336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.22.14004-14016.2005
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