Passive Immunization with Bovine Milk Containing Antibodies to a Cell Surface Protein Antigen-Glucosyltransferase Fusion Protein Protects Rats against Dental Caries

Cell surface protein antigen (PAc) and glucosyltransferases (GTF) of Streptococcus mutans are major colonization factors of the organism. We prepared bovine milk containing antibodies against a fusion of the saliva-binding alanine-rich region of PAc with the glucan-binding domain of GTF-I. This stud...

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Bibliographic Details
Main Authors: Mitoma, Morihide, Oho, Takahiko, Michibata, Naoko, Okano, Kaoru, Nakano, Yutaka, Fukuyama, Masataka, Koga, Toshihiko
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2002
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC127952/
https://ncbi.nlm.nih.gov/pubmed/11953419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2721-2724.2002
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