Passive Immunization with Bovine Milk Containing Antibodies to a Cell Surface Protein Antigen-Glucosyltransferase Fusion Protein Protects Rats against Dental Caries

Cell surface protein antigen (PAc) and glucosyltransferases (GTF) of Streptococcus mutans are major colonization factors of the organism. We prepared bovine milk containing antibodies against a fusion of the saliva-binding alanine-rich region of PAc with the glucan-binding domain of GTF-I. This stud...

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Detalhes bibliográficos
Main Authors: Mitoma, Morihide, Oho, Takahiko, Michibata, Naoko, Okano, Kaoru, Nakano, Yutaka, Fukuyama, Masataka, Koga, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127952/
https://ncbi.nlm.nih.gov/pubmed/11953419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.5.2721-2724.2002
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