Immunoglobulin G Monoclonal Antibodies to Cryptococcus neoformans Protect Mice Deficient in Complement Component C3

Passive administration of monoclonal antibodies (MAbs) to the capsular polysaccharide of Cryptococcus neoformans can alter the course of infection in mice. In a murine model of cryptococcal infection, immunoglobulin G1 (IgG1), IgG2a, and IgG2b switch variants of the anti-capsular 3E5 MAb prolong the...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Shapiro, Scott, Beenhouwer, David O., Feldmesser, Marta, Taborda, Carlos, Carroll, Michael C., Casadevall, Arturo, Scharff, Matthew D.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Fungal and Parasitic Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11953401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.5.2598-2604.2002
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!