Immunization with the RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Protects against Periodontal Bone Loss in the Rat Periodontitis Model

A major virulence factor of Porphyromonas gingivalis is the extracellular noncovalently associated complexes of Arg-X- and Lys-X-specific cysteine proteinases and adhesins designated the RgpA-Kgp complexes. In this study we investigated the ability of RgpA-Kgp as an immunogen to protect against P. g...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Rajapakse, P. Sunethra, O'Brien-Simpson, Neil M., Slakeski, Nada, Hoffmann, Brigitte, Reynolds, Eric C.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2002
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127921/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11953385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.5.2480-2486.2002
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